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Research · 2026

Circumflex — Neonatal Photoacoustic Oximeter

Two-quarter capstone: a miniaturized transesophageal photoacoustic oximetry probe to non-invasively measure pulmonary venous oxygen saturation in neonates with congenital heart disease.

Role: Capstone Team (Circumflex) — BIOE 141A/B

Overview

Neonates with congenital heart disease often need invasive measurements that extend NICU stays. As part of Team Circumflex (the BIOE 141A/B capstone), we designed the Esophageal Pulmonary Venous Oximeter (E-PVO): a flexible transesophageal probe positioned in the esophagus adjacent to the left atrium that uses photoacoustic sensing to non-invasively estimate pulmonary venous oxygen saturation — aiming to reduce length of stay in the NICU.

Highlights

  • Defined the clinical need and concept for a minimally invasive transesophageal photoacoustic oximeter for neonates.
  • Designed a flexible probe positioned adjacent to the left atrium to estimate pulmonary venous oxygen saturation.
  • Iterated the design across milestone reviews spanning requirements, prototyping, and validation planning.

Tech & topics

  • Medical Devices
  • Biosensors
  • Photoacoustics
  • Hardware
  • Neonatal Care